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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRK
All Species:
9.09
Human Site:
Y11
Identified Species:
16.67
UniProt:
P42685
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42685
NP_002022.1
505
58254
Y11
I
C
Q
R
L
W
E
Y
L
E
P
Y
L
P
C
Chimpanzee
Pan troglodytes
XP_518702
505
58217
Y11
I
C
Q
R
L
W
E
Y
L
E
P
Y
L
P
C
Rhesus Macaque
Macaca mulatta
XP_001112190
505
58228
Y11
I
C
Q
R
L
W
E
Y
L
E
P
Y
L
P
C
Dog
Lupus familis
XP_539091
505
57709
C18
H
L
R
R
W
L
P
C
A
G
R
E
P
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q922K9
512
58825
C18
Y
L
Q
P
F
L
P
C
W
S
Q
E
A
D
K
Rat
Rattus norvegicus
Q62662
506
58147
L12
C
M
R
L
W
A
Y
L
Q
P
F
L
P
C
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q02977
536
59984
D33
P
P
S
Q
Y
D
P
D
P
T
Q
L
S
G
A
Frog
Xenopus laevis
P13406
537
60828
P34
G
Y
R
Y
G
T
D
P
T
P
Q
H
Y
P
S
Zebra Danio
Brachydanio rerio
XP_695937
480
54879
K12
V
I
T
N
E
F
A
K
P
Q
N
R
E
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
A16
K
G
E
P
D
K
P
A
D
R
I
K
L
D
D
Honey Bee
Apis mellifera
XP_396043
451
51726
Nematode Worm
Caenorhab. elegans
NP_493502
507
57512
G13
G
K
E
D
P
P
P
G
A
T
S
P
V
H
T
Sea Urchin
Strong. purpuratus
NP_001135852
530
59779
K15
L
G
L
T
K
S
D
K
N
Y
N
P
S
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.6
80.5
N.A.
88.6
88.3
N.A.
N.A.
48.5
48.4
60.5
N.A.
56.8
51.6
50.4
56.6
Protein Similarity:
100
99.8
98
87.7
N.A.
92.9
93
N.A.
N.A.
64.7
64.2
74
N.A.
73.3
67.1
69.4
70.5
P-Site Identity:
100
100
100
6.6
N.A.
6.6
0
N.A.
N.A.
0
6.6
0
N.A.
6.6
0
0
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
6.6
6.6
N.A.
N.A.
6.6
26.6
20
N.A.
13.3
0
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
8
16
0
0
0
8
0
16
% A
% Cys:
8
24
0
0
0
0
0
16
0
0
0
0
0
8
24
% C
% Asp:
0
0
0
8
8
8
16
8
8
0
0
0
0
16
8
% D
% Glu:
0
0
16
0
8
0
24
0
0
24
0
16
8
8
0
% E
% Phe:
0
0
0
0
8
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
16
16
0
0
8
0
0
8
0
8
0
0
0
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
24
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
8
8
0
0
8
8
0
16
0
0
0
8
0
0
16
% K
% Leu:
8
16
8
8
24
16
0
8
24
0
0
16
31
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
0
16
0
0
0
0
% N
% Pro:
8
8
0
16
8
8
39
8
16
16
24
16
16
39
8
% P
% Gln:
0
0
31
8
0
0
0
0
8
8
24
0
0
0
0
% Q
% Arg:
0
0
24
31
0
0
0
0
0
8
8
8
0
0
0
% R
% Ser:
0
0
8
0
0
8
0
0
0
8
8
0
16
0
8
% S
% Thr:
0
0
8
8
0
8
0
0
8
16
0
0
0
0
8
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
16
24
0
0
8
0
0
0
0
0
8
% W
% Tyr:
8
8
0
8
8
0
8
24
0
8
0
24
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _